How is MRSA passed on? MRSA can be transmitted from person to person fairly easily, mainly via the hands. It is important to remember that MRSA rarely causes problems for fit and healthy people. Many people carry MRSA without knowing it and never experience any ill effects. (These people are said to be colonised with MRSA rather than being infected with it). In most cases, MRSA only poses a threat when it has the opportunity to get inside the body and cause an infection, for example via wounds or surgical scars.